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Professor Lillrank has conducted research on quality management in several service industries, such as software, telecom, airlines and retailing. He has been a pioneer in introducing industrial management methods to the study of health service production. He has co-founded the Institute of Healthcare Engineering, Management and Architecture (HEMA) at Aalto, and The Nordic Healthcare Group (NHG), a consultancy.

His research interests are within Health Systems Science, particularly service process analysis and improvement, knowledge integration, segmentation principles, value-based care, regional service supply systems, and frugal innovations. Professor Lillrank has recently published the seminal textbook: The Logics of Healthcare – The Practitioner’s Guide to Health Systems Science (Francis & Taylor 2018).